Toxic keratitis

Toxic keratitis : A fairly frequent entity characterized by toxicity of the corneal epithelium , caused by exposure to chemical substances ( alcohol , solvents) or topical drugs ( gentamicin , antivirals).


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  • 1 Symptoms
  • 2 Critical sign
  • 3 Other signs
  • 4 Diagnostic protocol
  • 5 Treatment protocol
  • 6 Follow-up
  • 7 Sources


  • Red eye.
  • Tearing.
  • Photophobia.
  • Blurry vision.
  • Decreased vision.

Critical sign

  • Superficial dotted keratitis, which is seen as a fine dotted line that occupies the entire cornea.

Other signs

  • Eyelid edema.
  • Chemosis.
  • Cilioconjunctival injection.

Diagnostic protocol

  1. History: history of exposure to chemical substances, or topical use of medications, generally for a long time and frequency.
  2. Biomicroscopy of the anterior segment, in slit lamp, with fluorescein staining: fine stippling on the entire corneal surface.
  3. If chemical exposure is suspected, check tear pH and if not neutral, treat as a chemical burn (see Cornealburn ).

Treatment protocol

  1. Eliminate the cause (suspend the topical medicine (s)).
  2. Fresh growths of saline, 3 times a day for 10 min.
  3. Oral antihistamines1 tablet every 8 hours.
  4. No occlusion.


  • Weekly, until improvement is observed.
  • Then monthly until full cure.


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