What is Imipramine?

Imipramine is used in the treatment of depression .

Sometimes it is given to children who bathe the bed.

What is Imipramine?

Imipramine is a tricyclic antidepressant , that is, composed of a 3-ring structure. It acts on the brain .

How is Imipramine taken?

Imipramine is taken orally . To reduce its side effects (especially daytime sleepiness) it is preferable to give it before going to sleep.

Side effects of Imipramine

Taking Imipramine can be associated with the appearance of serotonergic syndrome , an increase in the amount of Serotonin . In addition, the drug can increase the risks for the eyes and the sensitivity of the skin to the sun. It is important to pay close attention to the risk of heat stroke .

Other possible side effects of this drug include:

  • dizziness
  • drowsiness
  • dry mouth
  • excitement
  • headache
  • impotence
  • nausea
  • nightmares
  • dilation of the pupils
  • sensitivity to sunlight
  • sweating
  • fatigue
  • stomach problems
  • He retched
  • weakness
  • weight changes

It is good to contact your doctor immediately in case of:

  • rash
  • urticaria
  • itch
  • breathing difficulties
  • feeling of tightness in the chest
  • swelling of the mouth, face, lips or tongue
  • problems in the sexual sphere
  • chest pain
  • confusional state
  • constipation
  • fainting
  • rapid, slowed or irregular heart beat
  • temperature
  • difficult or frequent urination
  • hallucinations
  • compulsive behavior or other changes in behavior
  • muscle spasms in the neck or jaw
  • mood swings
  • panic attacks
  • annoying hearing disorders
  • convulsions
  • severe dizziness or drowsiness
  • sore throat
  • stomach ache
  • suicidal thoughts or behavior
  • swelling of the testicles
  • tremors
  • insomnia
  • trouble walking or balance
  • face or tongue tics
  • muscle stiffness
  • bleeding or bruising
  • aggravation of depression
  • yellowish discolouration of the skin

Warnings on the use of Imipramine

Imipramine can interfere with your ability to drive or operate dangerous machinery due to the dizziness it can trigger. Alcohol or other medications can aggravate this side effect of the drug.

It may be necessary to take Imipramine for at least 1-3 weeks for it to work . In any case, treatment should not be stopped suddenly without first talking to your doctor: the risk is the appearance of withdrawal symptoms.

Before starting to take the drug, however, you should inform your doctor:

  • of any allergies to the active substance, its excipients or any other medication or food;
  • of the medicines, phytotherapy and supplements taken , in particular MAO inhibitors (even if the treatment was interrupted in the previous 14 days), drugs for the thyroid gland, drugs that contain Methylene blue, Busipirone, Cimetidine, Fentanyl, Flecainide, Lithium, Methylphenidate, Phenothiazines, Propafenone, Quinidine, SSRI, SNRI, St. John’s Wort, Tramadol, Linezolid, Tryptophan, Barbiturates, Phenytoin, anticholinergics, sympathomimetics, Clonidine, Guanetidine or Guanfacine;
  • in case of a recent heart attack ;
  • if you suffer (or have suffered) from diabetes, alcoholism, hyperthyroidism, glaucoma, increased eye pressure, heart, kidney or liver problems, diabetes, seizures, porphyria, urination problems, suicidal thoughts or behavior, bipolar disorder or other psychiatric illnesses;
  • if you are taking electroshock therapy ;
  • planned surgery ;
  • if you are pregnant or breastfeeding .

It is also necessary to inform surgeons and dentists about taking Imipramine.

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