What is Imipenem +Cilastatina?

Imipenem + Cilastatin is used to treat certain bacterial infections .

What is Imipenem + Cilastatina?

Imipenem + Cilastatin works by killing bacteria : it blocks the formation of their cell wall.

How is Imipenem + Cilastatina taken?

Imipenem + Cilastatin can be administered through vein infusions (drip) or intramuscular injections.

Side effects of Imipenem + Cilastatin

Long-term or repeated use of Imipenem + Cilastatin can lead to the appearance of a second infection .

Other possible side effects include:

  • mild diarrhea
  • nausea
  • He retched
  • mild pain, swelling or redness around the injection site

It is important to contact a doctor immediately in case of:

  • rash
  • urticaria
  • itch
  • breathing difficulties
  • feeling of tightness or chest pain
  • swelling of the mouth, face, lips or tongue
  • blood in the stool
  • dark urine
  • reduced urination
  • fast or irregular heart beat
  • fever, chills or sore throat
  • hearing loss
  • joint pain or sensitivity
  • changes in mood or behavior
  • numbness or tingling in the skin
  • red, swollen, blistered or peeling skin
  • convulsions
  • severe diarrhea
  • severe stomach pain or cramps
  • shortness of breath
  • swollen hands or feet
  • swelling or redness at the injection site
  • tremors or abnormal muscle movements
  • bruising or bleeding
  • excessive tiredness or weakness
  • vaginal discharge or unusual bad odors
  • swelling or sensitivity of the veins
  • white patches in the mouth
  • yellowish discolouration of the skin

Contraindications and warnings on the use of Imipenem + Cilastatina

Imipenem + Cilastatin is not indicated in case of heart block (alteration of the electrical impulses of the heart), severe shock and taking Probenecid. It may not be indicated in children weighing less than 30 kg and if associated with kidney problems or nervous system infections.

Before administration it is important to inform your doctor:

  • of any allergies to the active substance, to its excipients, to any other drug (in particular to antibiotics or anesthetics), to foods or other substances;
  • of the medicines, phytotherapy and supplements taken, in particular Ganciclovir, Amiodarone, beta-blockers, Cimetidine, Mexiletina, Probenecid, Succinylcholine, Divalproex, Valproic Acid and any drug that may increase the risk of convulsions;
  • if you suffer (or have suffered) from kidney, liver or heart problems, high blood pressure, seizures or central nervous system problems;
  • if you are in shock;
  • if you have been very sick or very weak;
  • in case of dialysis ;
  • if you are pregnant or breastfeeding;

Imipenem + Cilastatina may impair your ability to drive and operate dangerous machinery . This side effect can be aggravated by alcohol and some medications.

It is important to inform doctors, surgeons and dentists about taking Imipenem + Cilastatin.

mipenem + Cilastatin is used to treat certain bacterial infections .

What is Imipenem + Cilastatina?

Imipenem + Cilastatin works by killing bacteria : it blocks the formation of their cell wall.

How is Imipenem + Cilastatina taken?

Imipenem + Cilastatin can be administered through vein infusions (drip) or intramuscular injections.

Side effects of Imipenem + Cilastatin

Long-term or repeated use of Imipenem + Cilastatin can lead to the appearance of a second infection .

Other possible side effects include:

  • mild diarrhea
  • nausea
  • He retched
  • mild pain, swelling or redness around the injection site

It is important to contact a doctor immediately in case of:

  • rash
  • urticaria
  • itch
  • breathing difficulties
  • feeling of tightness or chest pain
  • swelling of the mouth, face, lips or tongue
  • blood in the stool
  • dark urine
  • reduced urination
  • fast or irregular heart beat
  • fever, chills or sore throat
  • hearing loss
  • joint pain or sensitivity
  • changes in mood or behavior
  • numbness or tingling in the skin
  • red, swollen, blistered or peeling skin
  • convulsions
  • severe diarrhea
  • severe stomach pain or cramps
  • shortness of breath
  • swollen hands or feet
  • swelling or redness at the injection site
  • tremors or abnormal muscle movements
  • bruising or bleeding
  • excessive tiredness or weakness
  • vaginal discharge or unusual bad odors
  • swelling or sensitivity of the veins
  • white patches in the mouth
  • yellowish discolouration of the skin

Contraindications and warnings on the use of Imipenem + Cilastatina

Imipenem + Cilastatin is not indicated in case of heart block (alteration of the electrical impulses of the heart), severe shock and taking Probenecid. It may not be indicated in children weighing less than 30 kg and if associated with kidney problems or nervous system infections.

Before administration it is important to inform your doctor:

  • of any allergies to the active substance, to its excipients, to any other drug (in particular to antibiotics or anesthetics), to foods or other substances;
  • of the medicines, phytotherapy and supplements taken, in particular Ganciclovir, Amiodarone, beta-blockers, Cimetidine, Mexiletina, Probenecid, Succinylcholine, Divalproex, Valproic Acid and any drug that may increase the risk of convulsions;
  • if you suffer (or have suffered) from kidney, liver or heart problems, high blood pressure, seizures or central nervous system problems;
  • if you are in shock;
  • if you have been very sick or very weak;
  • in case of dialysis ;
  • if you are pregnant or breastfeeding;

Imipenem + Cilastatina may impair your ability to drive and operate dangerous machinery . This side effect can be aggravated by alcohol and some medications.It is important to inform doctors, surgeons and dentists about taking Imipenem + Cilastatin.

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