What is cefepima used for?

The cefepime is an antibiotic (fourth generation cephalosporin) pursuing an activity similar to ceftazidime . It acts on Enterobacter cloacae, Pseudomonas aeruginosa and Staphylococcus aureus.
It is able to inhibit the synthesis of the bacterial wall of both Gram-positive and Gram-negative microorganisms, compromising its structural properties and therefore causing death.

What is cefepima used for?

It is used to treat the following infections :

  • pneumonia
  • infections of the reproductive organs, urinary tract and kidneys
  • infections in people with low white blood cell counts (neutropenia)
  • dermatological infections
  • blood infections caused by bacteria (bacteremia)
  • meningitis (in children)
  • abdominal infections

How is cefepima taken?

It is marketed in the form of a powder for solution for injection or infusion and is administered by intramuscular injection, slow injection into a vein or through a small cannula into a vein. Usually the treatment lasts 7-10 days, depending on the type of infection.

Side effects of cefepima

The recognized side effects are many. The most common are:

  • positive result of the Coombs test (a test that highlights some problems in the blood)
  • problems with blood clotting (easy bruising)
  • anemia
  • inflammation or burning or pain of the vein in the injection area
  • discharge of diarrhea
  • liver problems
  • rash

Less common side effects are:

  • mushroom infection in the mouth
  • infections in the vagina
  • changes in the number of white blood cells in the blood (febrile state, chills and sore throat)
  • headache
  • inflammation of the large intestine (discharge of diarrhea , usually with blood and mucus, pain in the stomach and fever)
  • feeling sick and retching
  • hives , itching
  • kidney problems
  • temperature

Rarer side effects are instead:

  • severe allergic reactions (sudden swelling of the face, throat, lips or mouth which can make breathing and swallowing difficult; sudden swelling of the hands, feet and ankles).

Other possible side effects:

  • fungal infections
  • dizziness
  • seizure symptoms
  • shortness of breath
  • abdominal pain
  • constipation

Contraindications and warnings of cefepima

If you are pregnant or planning to become pregnant, or if you are breast-feeding, you should seek advice from your doctor before taking this medicine. Particular care should be taken when administering it to patients suffering from kidney problems; in allergy sufferers, the elderly, with bowel problems (particularly inflammatory, colitis type).

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