The cephalexin is an antibiotic belonging to the family of cephalosporins of the first generation.
It acts very similar to penicillins, with antimicrobial activity comparable – although less powerful – to that of Cephalotin (another first generation cephalosporin). Like other cephalosporins, this drug also inhibits bacterial growth by interfering with the synthesis of the bacteria wall.
Like penicillins, cephalosporins instead bind to the transpeptidase enzymes that are used to create the bonds between the peptidoglycan chains (the polymer necessary for the formation of the bacterial wall): the inhibition of the activity of the transpeptidases, compromises the stability of the wall, leading to the death of cells in the growth phase.
What is Cefalexin used for?
It is prescribed for the treatment of skin, respiratory and urinary tract infections, otitis media and other infections. In the case of more serious infections, parenteral cephalosporin treatments are preferred.
How is Cefalexine taken?
Cefalexin is administered orally (capsules, tablets or suspension).
Side effects of Cefalexin
The undesirable effects detected following its use are sometimes considered “clinically relevant”, and often depend on both the duration and the prescribed therapeutic doses. Among these we must certainly mention:
- feeling sick
- discharge of diarrhea
- allergic reactions.
Contraindications and warnings of Cefalexin
Particular attention should be paid to subjects with impaired renal function. In case of persistent diarrhea it is advisable to notify your doctor, who will be able to advise the patient appropriately and suggest any additional therapies. Although experimental studies do not currently show serious side effects for the fetus, it would be advisable to limit the use of Cefalexin – in pregnant women – to only cases of real need and in any case under strict specialist medical supervision.