The Rivaroxaban is used in the treatment of both preventive and symptomatic deep vein thrombosis , in the reduction of risk of stroke , as well as in the prevention and treatment of the formation of blood clots .
What is Rivaroxaban?
Rivaroxaban directly inhibits coagulation factor Xa , thus blocking the formation of blood clots.
How is Rivaroxaban taken?
Rivaroxaban is taken orally in the form of tablets.
Side effects of Rivaroxaban
Rivaroxaban can cause slight bleeding.
A doctor should be contacted immediately in case of:
- feeling of tightness in the chest
- blood in your stool or dark stool
- changes in the production of urine or dark, pink or red urine
- blood in the sputum
- persistent fever, chills or sore throat
- pain, swelling or leakage of material from wounds
- red, swollen or peeling skin
- joint problems
- symptoms of cerebral hemorrhage
- swelling of the face, eyes, lips, tongue or throat
- breathing difficulties
- low pressure
- unexplained swelling
- bleeding or bruising
- coffee-like vomiting
Contraindications and warnings on the use of Rivaroxaban
The intake of Rivaroxaban is contraindicated to a number of subjects , such as those who have suffered some types of bleeding and bleeding disorders caused by liver diseases, those with an artificial heart valve and those who suffer from some kidney or liver problems .
The drug must also not be taken by those who are being treated with other coagulants, Lopinavir, Abciximab, Bivalirudina, Alteplase, Boceprevir, Carbamazepina, Cobicistat, Conivaptan, Dabigratan, Desirudina, Enzalutamide, Eptifibatide, Idantoine, Indinavir, Itracon, Itracon Fenobarbital, Posaconazole, Rifamicine, Ritonavir, Saquinavir, Telaprevir, Tirofiban, Voriconazole and Hypericum.
Before stopping treatment, it is necessary to seek medical advice .
Before starting a Rivaroxaban treatment, you should inform your doctor:
- of any allergies to the active substance, its excipients, other medicines , foods or to any other substance;
- of the medicines, phytotherapy and supplements taken , in particular other coagulants, Abciximab, Alteplase, Aspirin or Fans, Bivalirudin, Dabigatran, Desirudin, Eptifabide, platelet inhibitors, Tirofibran, Boceprevir, Clarithromycin, Cobicistat, Conivaptan, Eritromycin, Eritromycin , Itraconazole, Ketoconazole, Lopinavir, Nelfinavir, Posaconazole, Ritonavir, Saquinavir, Telaprevir, Voriconazole, Carbamazepina, Enzalutamide, Idantoine, Fenobarbital, Rifamycin or Hypericum;
- if you have suffered or still suffer from bleeding or clotting disorders, high blood pressure, blood vessel problems, anemia or other hematological diseases, low platelets or other problems with your platelets, kidney or liver disease, stroke , gastrointestinal ulcers , hereditary diseases;
- if you are at risk of bleeding;
- if you are planning surgery ;
- if you suffer from kidney problems and are being treated with Amiodarone, Azithromycin, Chloramphenicol, Cimetidine, Diltiazem, Dronedarone, Erythromycin, Felodipine, Quinidine, Ranolazine or Verapamil;
- if you are pregnant or breastfeeding .
In the case of spinal or epidural procedures during treatment with Rivarobaxan it is good to warn your doctor if you have symptoms of nerve problems, such as back pain, muscle weakness, paralysis, loss of bowel or bladder control or numbness.
Your doctor, surgeon or dentist should be informed immediately of the Rivaroxaban intake.