What is Rifampicin?

The Rifampicin is used primarily in the treatment of tuberculosis . Furthermore, it is used to prevent the spread of the meningitis bacterium , when the bacterium has already colonized the nasal cavity or the throat, without however giving rise to the disease. Rifampicin in any case is not indicated in the treatment of meningitis .

What is Rifampicin?

The action of Rifampicin involves the elimination of bacteria sensitive to its action , or the inhibition of the synthesis of their RNA , which therefore blocks their growth.

How is Rifampicina taken?

Rifampicin is usually given by an injection directly into the vein . It is also possible to prescribe its oral intake , usually in the form of capsules.

Side effects of Rifampicin

Rifampicin can give a red color to urine, sweat, saliva and tears. It can also indelibly color soft contact lenses.

Its other potential side effects include:

  • drowsiness
  • gas
  • headache
  • heartburn
  • diarrhea
  • dizziness
  • changes in the menstrual cycle
  • mild pain or cramps in the stomach

When Rifampicin triggers one of the following side effects, a doctor should be contacted immediately:

  • rash
  • swelling of the arms , face or legs
  • dark urine , loss of appetite, pale stools or jaundice
  • bruising or bleeding
  • urticaria
  • itch
  • breathing difficulties
  • changes in the amount of urine produced
  • confusion
  • fever, chills or sore throat
  • pain or swelling in the joints
  • muscle pain or weakness
  • nausea
  • feeling of tightness in the chest
  • swelling of the mouth, face, lips or tongue
  • urine or dark stools
  • blood in the urine or stool
  • pain, swelling or redness at the injection site
  • red, swollen, blistered or peeling skin
  • diarrhea, cramps or stomach pain
  • shortness of breath
  • tiredness or weakness
  • vision problems
  • He retched

Warnings on the use of Rifampicin

The Rifampicin should never be taken together with Atanazivir, Cabazitaxel, Darubinavir, Delavirdine, Dronedarone, etravirine, Fosmprenavir, Lurasidone, nifedipine, Praziquantel, Ranolazine, saquinavir, Tripanavir, inhibitors of the receptor tyrosine kinase or voriconazole.

Taking it on may impair your ability to drive or operate dangerous machinery . Alcohol use or medication intake can aggravate this effect.

It can also decrease the effectiveness of hormonal contraceptives, affect blood sugar levels and interfere with some laboratory tests.

Your doctor should always be informed before starting Rifampicin therapy:

  • of any allergies to the active substance, to its excipients, to other drugs (in particular to rifamycins) or to any food
  • of the medicines, phytotherapics and supplements taken , in particular Atanazivir, Cabazitaxel, Darubinavir, Delavirdina, Dronedarone, Etravirina, Fosmprenavir, Lurasidone, Nifedipina, Praziquantel, Ranolazina, Saquinavir, Tripanavir of the Vaccininator cardiovascular problems, diabetes or HIV, medicines against high levels of iron or uric acid or low levels of sodium or vitamin D, medicines against nausea and vomiting, pain relievers, anticonvulsants, medicines for insomnia, medicines for the thyroid gland, immunosuppressants, psychotropic drugs or medicines against infections;
  • if in the past you have suffered or still suffer from adrenal problems, porphyria, diabetes, liver disease, inflammation or obstruction of the biliary tract;
  • if you are pregnant or breastfeeding .

Your doctor, dentist, surgeon should always be informed of ongoing Rifampicin treatment.

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