What is febuxostat?

The febuxostat is used to prevent gout attacks.

What is febuxostat?

The febuxostat works by reducing the concentration of uric acid generated by the body (derives from protein catabolism). To do this it hinders the enzyme xanthine oxidase.

How is febuxostat taken?

The febuxostat is administered orally, usually in the form of tablets to be administered once a day.

Your doctor may increase the dosage after evaluating uric acid levels after two weeks of treatment.

Side effects of febuxostat

The febuxostat can increase the levels of liver enzymes in the blood, this effect can be the symptom of liver injury.

Among its other possible side effects we also find:

  • nausea
  • articolar pains

It is essential to notify a doctor immediately in the presence of:

  • rash
  • urticaria
  • itch
  • breathing problems
  • feeling of tightness in the chest
  • swelling of the mouth, face, lips or tongue
  • shortness of breath
  • trouble speaking
  • dizziness or fainting
  • weakness or numbness of an arm or leg

Contraindications and warnings

Before taking febuxostat it is essential to always tell your doctor:

  • of possible allergies to the active substance, to its excipients, to any other medicine, to foods or other substances
  • of the drugs, phytotherapy and supplements taken, specifically mentioning azathioprine, mercaptopurine, theophylline and chemotherapy
  • if you suffer (or have suffered) from chest aches, tumors, Lesch-Nyhan syndrome or heart, kidney or liver disease
  • in the presence of stroke
  • in the presence of transplants
  • if you are pregnant or breastfeeding

It may take several months for therapy to give results; during an initial phase, gout attacks may also increase, making it necessary to take other medicines. In any case, the treatment must never be stopped without the doctor indicating it.

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