What is Ezetimibe?

Ezetimibe is used mainly in the treatment of high cholesterol .

What is Ezetimibe?

Ezetimibe works by reducing the amount of cholesterol absorbed by the body.

How is Ezetimibe taken?

Ezetimibe is taken by mouth . Sometimes it is taken in combination with other medicines to minimize the cholesterol concentration.

It must be taken at the same time as a correct diet and physical activity program.

Side effects of Ezetimibe

In a few cases, cholesterol-lowering drugs can lead to myalgia and rhabdomyolysis , thus increasing the danger of kidney failure.

Among other possible side effects of ezetimibe we also find:

  • numbness or tingling;
  • slight stomach pain, diarrhea ;
  • feeling of tiredness ;
  • headache;
  • dizziness ;
  • depression;
  • stuffy or runny nose, symptoms of a cold;
  • back pain or joint pain;
  • cough.

It is best to notify a doctor immediately in the presence of:

  • rash ;
  • urticaria ;
  • itching ;
  • breathing problems;
  • feeling of tightness or chest pain;
  • swelling of the mouth, face, lips or tongue;
  • unusual weakness, sensitivity or muscle pain;
  • nausea ;
  • stomach pain;
  • low fever;
  • loss of appetite;
  • dark urine ;
  • clay-colored stools;
  • jaundice ;
  • pancreatitis;
  • temperature;
  • throat pain and head pain related to severe skin rash ;
  • blisters and peeling of the epidermis.

Contraindications and warnings on the use of Ezetimibe

Ezetimibe should not be taken together with Colestyramine, Colestipol or Colesevelam: you must wait at least 4 hours after taking one of these medicines before taking it, or take it at least 2 hours before these medicines.

In addition, Ezetimibe should not be taken in combination with Fenofibrate or Statine.

Before taking it is essential to warn the doctor:

  • of allergies to the active substance, its excipients, other medicines, foods, or other substances;
  • the drugs, phytotherapy and supplements taken, specifically mentioning steroids and hormones (also the contraceptive pill), Colestyramine, Colestipol, Colesevelam, Gemfibrozil, Cyclosporine and anticoagulants;
  • if you suffer (or have suffered) from kidney disease or thyroid problems ;
  • if you are pregnant or breastfeeding .

Up to 2 weeks of treatment may be needed before seeing improvements in cholesterol levels

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