What is Erythromycin for?

Erythromycin is an antibiotic belonging to the family of macrolide (a chemical compound consisting of a macrocyclic ring) and its action is mainly bacteriostatic: acts by blocking the growth of bacteria. Only at high concentrations, however, does it kill them. In particular, macrolides work by interfering with the creation of proteins in bacteria.

The microbes against which Erythromycin is active include Streptococcus pyogenes, Diplococcus pneumoniae, Mycoplasma pneumoniae, Chlamydia trachomatis, Haemophilus influenzae, Legionella pneumophila, Staphylococcus aureus, Chlamydia trachomatis, Listeria monocytogenes, Trepidium, jeep. and Leptospira.

What is Erythromycin for?

Erythromycin is used to treat infections with bacteria sensitive to its action. It is indicated, for example, against some forms of pneumonia and other respiratory infections, in the case of otitis media, legionellosis (lung infection), infections of the urogenital tract, enteritis, diarrhea, anthrax and leptospirosis (known as “fever from field”.)

In addition, this antibiotic can be used in case of severe acne , conjunctivitis or corneal infections, some endocarditis, whooping cough, erythrasma (infection in the wet folds of the skin), diphtheria sepsis, lymphogranuloma venereal, venereal ulcer, non-gonococcal urethritis resistant to dossycycline or azithromycin as an aide in the treatment of Corynebacterium diphteria diphtheria and, in pregnant women, against genital Chlamydia infections.

Finally, Erythromycin can be used to replace penicillins in people allergic to these antibiotics.

How is Erythromycin taken?

Erythromycin can be taken orally (on an empty stomach) or intravenously . There are also products, such as those used in the case of acne, to be applied to the skin. Being an antibiotic it should only be taken with medical advice.

The method and time of application depends on the age and individual needs.

Side effects of Erythromycin

The most common side effects associated with the use of Erythromycin concern the digestive system; for example it is:

  • nausea ;
  • He retched;
  • diarrhea ;
  • anorexia .

To these can be added cardiovascular problems (such as prolongation of the QT interval, time needed for the ventricle to contract, and ventricular tachycardia), nightmares, skin irritation.

Other dermatological problems, such as:

  • heartburn;
  • Dryness;
  • flaking;
  • itching;
  • Rashes.

Other possible side effects are:

agranulocytosis, cholestatic hepatitis, increased alkaline phosphatase, bilirubin and transaminases, tinnitus and other temporary hearing problems, serum sickness, myasthenic syndrome, superinfections caused by resistant microorganisms or following repeated and prolonged treatments, pseudomembranous colitis, hypersensitivity and , in children, hypothermia.

Contraindications and warnings on the use of Erythromycin

Erythromycin intake is contraindicated in case of hypersensitivity and familiarity for:

  • allergic diseases;
  • liver failure;
  • yellowish discoloration of the skin;
  • severe liver disease;
  • biliary obstruction;
  • porphyria;
  • systemic lupus erythematosus.

This antibiotic can also interact with other drugs, including:

  • Ergot alkaloids;
  • alfentanil;
  • Alprazolam;
  • Astemizole, Cisapride, Terfenadine and Pimozide;
  • Atorvastatin;
  • bromocriptine;
  • Buspirone;
  • Calcium antagonists;
  • Carbamazepine;
  • cerivastatin;
  • quinidine;
  • Cyclosporine;
  • cimetidine;
  • Chloramphenicol and Lincosamides;
  • clozapine;
  • Colchicine;
  • Oral contraceptives;
  • Digoxin;
  • Disopyrimide;
  • Felodipine;
  • Phenytoin;
  • Fexofenadine;
  • Guarana;
  • Lovastatin;
  • Methylprednisolone;
  • Midazolam and Triazolam;
  • penicillins;
  • Repaglinide;
  • Sildenafil;
  • Simvastatin;
  • Tacrolimus;
  • Theophylline;
  • valproate;
  • Verapamil;
  • vinblastine;
  • Warfarin;
  • Zopiclone.

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