What Is Bazedoxifene

Bazedoxifene is a remedy used to relieve symptoms after menopause, especially the heat that feels in the region of the face, neck and chest. This medicine works by helping to restore adequate levels of estrogens in the body when progesterone treatment is not appropriate.

In addition, Bazedoxifene can also be used to treat common postmenopausal osteoporosis, reducing the risk of fractures, especially in the spine. It is still being studied as a way to prevent the growth of tumors in the breast, and may help in the treatment of breast cancer.


Bazedoxifene has not yet been approved by Anvisa in Brazil, and can only be found in Europe or the United States under the trade names Osakidetza, Duavee, Conbriza or Duavive, for example.

How to take

Bazedoxifene should only be used after menopause in women with uterus, at least 12 months since the last menstrual period. The dose can vary in each case and therefore should be indicated by the doctor. However, the recommended dose in most cases is:

  • 1 tablet daily with 20 mg of Bazedoxifene.

In case of forgetfulness, take the missed dose as soon as you remember, or take the following case if it is too close to the next hour, and you should avoid taking two tablets in less than 6 hours.

Possible side effects

Some of the most common side effects of this medication include frequent candidiasis, belly pain, constipation, diarrhea, nausea, muscle spasms, and increased triglycerides in the blood test.

Who should not take

Bazedoxifene is contraindicated for women with:

  • Hipersensibility to any of the formula’s components;
  • Presence, suspicion or history of breast, endometrial or other estrogen-dependent cancer;
  • Undiagnosed genital bleeding;
  • Untreated uterine hyperplasia;
  • History of thrombosis;
  • Blood diseases;
  • Liver disease;
  • Porphyria.

In addition, it should not be used by women who are not yet in menopause, especially if there is risk of pregnancy.

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