How Does Oxybutynin Work?

Oxybutynin is employed in therapies for urinary tract disorders such as urinary incontinence, urgency and frequent urination in unstable bladder conditions, idiopathic overactive bladder, neurogenic bladder disorders. From five years of age , it is also used in the pediatric population.

How does oxybutynin work?

Ossibutinin is a drug capable of inhibiting the effects of stimulations at the level of the parasympathetic autonomic nervous system, as it is an anticholinergic active on muscarinic receptors. This drug is used orally, because of its antispasomodic properties .

How is oxybutynin administered?

Ossibutinin is administered orally .

Side effects of oxybutynin

The potential side effects related to taking Oxybutynin concern gastrointestinal disorders, nervous system disorders, ocular and skin disorders.

Gastrointestinal disorders include:

  • dry mouth
  • constipation
  • nausea
  • abdominal discomfort
  • diarrhea
  • He retched

Nervous system disorders include:

  • headache
  • dizziness
  • drowsiness
  • convulsions
  • restlessness

Eye disorders include:

  • blurred vision
  • dilation of the pupils
  • dry eye
  • intraocular hypertension
  • induction of glaucoma (narrow angle glaucoma)

Among the skin disorders we report:

  • dry skin
  • rash
  • urticaria
  • angioedema
  • photosensitivity

Cognitive effects such as anxiety, hallucinations, confusion, paranoia have been reported among elderly patients . There are also potential cardiac, vascular and urinary tract disorders. Among the former, tachycardia and cardiac arrhythmia were found; among vascular pathologies facial redness is possible (more marked in children than in adults); difficulties with urination and urinary retention have been reported among urinary tract disorders .

Contraindications and warnings on the use of oxybutynin

If Oxybutynin is taken at the same time as other anticholinergic agents, great care must be taken as potentiation of its anticholinergic effects may occur . Since it reduces gastric mobility , it can influence the absorption of other drugs.

Taking Oxybutynin can induce drowsiness and blurred vision , therefore patients should be properly informed of the possible negative effects on their ability to drive, on the use of machinery or on the performance of work that requires particular attention.

Since the data regarding the use of oxybutynin in pregnancy are not adequate, it is good that expectant women do not take the drug unless it is strictly necessary. The use of oxybutynin by breastfeeding women is not recommended , since the drug is excreted via breast milk.

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