The Methotrexate is used to treat certain types of breast cancer , the skin , the head and neck or lung .It is also used in the treatment of severe forms of psoriasis and rheumatoid arthritis .It is usually used as an alternative to other medicines, when the latter have not given benefits.
What is Metrotrexate?
Methotrexate hinders the development of certain cells , specifically those that multiply rapidly, such as cancer cells, bone marrow cells and skin cells.
How is Metotrexate taken?
Methotrexate can be taken orally or by injections (usually intramuscular or in the vein). It can be associated with other medicines.
Usually it is taken 1 or 2 times a week. Daily intake can have very serious consequences.
Side effects of Metrotrexate
Methotrexate interferes with the growth of certain cells of the immune system and reduces the clotting ability of the blood. It can also have serious side effects on the liver, lung and kidneys.
Among its possible side effects we also find:
- vomiting and stomach upset
- head pain, dizziness and feeling tired
- clouded view
It is best to stop the medicine and notify your doctor immediately in the presence of:
- dry cough, shortness of breath
- diarrhea , vomiting or white patches or plaques in the mouth or on the lips
- blood in the urine or stool
- swelling, rapid weight gain, poor or absent urination
- fever, chills, aches or flu symptoms
- pallor, bruising, bleeding, weakness, feeling light-headed
- liver problems
- severe skin reactions
Warnings on the use of Metotrexate
Before starting Metotrexate therapy, it is essential to tell your doctor:
- of possible allergies to the active substance, its excipients or any other medication or food;
- drugs, phytotherapy and supplements taken, specifically anticoagulants, beta blockers, digitalis glycosides, Theophylline and corticosteroids;
- in the event that you suffer (or have suffered) from alcoholism, cirrhosis or other liver problems, blood problems (for example anemia or leukopenia) or bone marrow, folate deficiencies, pneumonia or other lung diseases, gastric ulcers o infections;
- if you are having radiation therapy ;
- in the presence of pregnancy or breastfeeding (before starting therapy there is a need to do a pregnancy test and during treatment you must use contraceptive methods even if you are a man, then continuing for at least 90 days or 1 cycle of ovulation after stopping the medicine