What Is Cutaneous Larva Migrans;Treatment,Prevention And Guideline

Cutaneous larva migrans is considered at this point because it’s most common cause is Ancylostoma braziliense, although it may be produced by a variety of other helminths. It is characterized by an erythematous, serpiginous, intracutaneous track or burrow, the anterior end of which is observed to migrate at the rate of 1 to 2 cm. per day. There is often intense irritation, and secondary infection may result from scratching. This migration is due to the infective larva of A. braziliense (the cat and dog hookworm), which does not viscerally in man but wanders around in the skin. This migration may last for 2 to 50 weeks before the larva dies. Rarely some larval reach the lungs, causing high eosinophilia and patchy pulmonary infiltration.

Patients are often infected by lying on beaches contaminated by dog or cat feces. The feet, legs,and hands are the most common sites, and the appearance of the lesion is usually diagnostic. It is virtually impossible to remove the larva from the skin.

Ancylostoma braziliense is found in the southern United States, Central America and tropical South America, as well as in tropical Africa and parts of the Far East, especially the Malay peninsula. There have been several reports of the worm maturing in the gut of man and eggs appearing in the feces, so there is not an absolute host specificity. Two other dog hookworms, Uncinaria stenocephala and Ancylostoma caninum, can produce similar lesions. Occasionally the ground itch of the two common human hookworms may persist and resemble creeping eruption in immune subjects.

The larva migrans track of Strongyloides ster-coralis tends to be a short line, erythematous and rapidly moving (larva currens). Rodent Strongyloides may produce similar lesions but no mature worms. A form of myiasis with the horse bot fly maggot (Gasterophilus) can produce a larger deeper migrating form of cutaneous larva migrans.

Treatment of Cutaneous Larva Migrans

Thiabendazole by mouth, 25 mg. per kilogram per day for two days, is usually effective. If not, the dose can be doubled and repeated. Alternatively, the advancing end of the burrow can be treated with topical thiabendazole sprinkled on elastoplast or in a cream containing 15 per cent thiabendazole powder in a hydrosoluble base. This drug has completely superseded the other, more unsatisfactory treatments such as ethyl chloride spray and Hetrazan.

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