What Is Bupivacaine;Uses, Side Effects And Contraindications

Bupivacaine is the active substance of an anesthetic medicine known commercially as Novocaine.This injectable drug is indicated for local anesthesia, especially before simple surgeries. Its action is to inhibit the conduction of nerve impulses to the brain thus reducing the perception of pain.

What Is Bupivacaine;Uses, Side Effects And Contraindications

Common Uses of Bupivacaine

Local or regional anesthesia or analgesia in surgical procedures (including oral surgery), diagnostic and therapeutic procedures, and obstetric procedures.
  • Bupivacaine will be given to you by a doctor with the necessary knowledge and experience in the epidural anesthetic technique.
  • The medicine is for single use only.
  • The medicine may be given before surgery (smaller or larger) or during labor.
  • In minor surgeries, the injection will be given near the operation site on the body.
  • The medication will prevent the pain and cause numbness that will gradually disappear after the end of the operation.
  • In larger surgeries or deliveries you may be given an injection in the back that will take a few minutes.
  • This will prevent pain and cause numbness in the lower body, lasting normally 3 to 4 hours.
  • In most cases, one dose is sufficient but other doses may be necessary if the surgery is prolonged.

Bupivacaine Side Effects

Anxiety; somnolence; dizziness; tremor; blurred vision; decreased pressure;arrhythmia; respiratory paralysis; decreased ventilation.

Contraindications of Bupivacaine

Pregnancy risk C ; women in the lactation phase; children under 12 years of age;Hipersensibility to any of the formula’s components.

Bupivacaine Use mode


  • Lumbar region : Apply 50 to 100 mg (10 to 20 ml) of Bupivacaine. Give additional doses of 3 to 5 ml.
  • Caudal region : Apply 75 to 150 mg (15 to 30 ml) of Bupivacaine.
Adverse Effects / side effects of Bupivacaine 5mg
Very common (> 1/10)
Cardiac disorders: hypotension, bradycardia
Gastrointestinal disorder: nausea
Common (> 1/100 <1/10)
Nervous system disorder: headache after postural dural puncture
Gastrointestinal disorder: vomiting
Urinary and renal disorders: urinary retention, urinary incontinence
Uncommon (> 1/1000 <1/100)
Nervous system disorders: paresthesia, paresis, dysesthesia
Musculoskeletal disorders of connective tissue and bone: muscle weakness, low back pain
Rare (<1 / 1,000)
Cardiac disorder: cardiac arrest
Immune system disorders: allergic reactions, anaphylactic shock
Nervous system disorders: total involuntary spinal block, paraplegia, paralysis, neuropathy,
Respiratory tract: respiratory depression


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