What Is Atroveran;Uses,Side Effects And Indication

Atroveran Compound is an analgesic and antispasmodic medication indicated for painful processes and colic. Papaverine hydrochloride, sodium dipyrone and the fluid extract of Atropa belladonna are the major components of Atroveran Compound. The Atroveran Compound can be found in tablet form (with 6 or 20 tablets) or in solution (30 ml).

Indications of Atroveran Compound

Analgesic and antispasmodic

Contraindications of Atroveran Compound

Patients who present allergy to any compound atroveran substance. Patients with acute angle-closure glaucoma, prostate hypertrophy, and individuals using narcotics, hypnotic medications, and barbiturates.

The product is contraindicated for patients who have a history of hypersensitivity to any of the components of the formula.

Contraindicated in patients with acute angle glaucoma , prostatic hypertrophy, the use of dipyrone, in cases of tonsillitis or any other condition of the bucopharyngeal, should be given extra caution; This pre-existing condition may mask the first symptoms of agranulocytosis (agranulocytic angina ), a rare but possible occurrence when using a product containing dipyrone. Its use should be avoided in the first three months and the last six weeks of pregnancy and, even outside these periods, dipyrone should only be given to pregnant women in cases of absolute necessity.

Patients with asthma or chronic respiratory infections, as well as patients with hypersensitivity to any substance, may develop shock. In patients with hematopoietic disorders, dipyrone should only be administered under medical control.

The product should not be given to patients who use narcotic, hypnotic and barbiturate medication.

During treatment, it is recommended to avoid drinking alcohol.

Adverse effects of Atroveran Compound

When used in high amounts, the product may cause nausea, tachycardia, dizziness and facial congestion. Papaverine base often causes elevation of plasma alkaline phosphatase, indicative of hepatotoxicity. The most serious, but quite rare, are shock and changes in blood components (agranulocytosis, leukopenia and thrombocytopenia). In occasional situations, especially in patients with a history of pre-existing kidney disease or in cases of overdose, there may be transient renal disorders with oliguria or anuria, proteinuria and interstitial nephritis. Asthma attacks may be observed in patients predisposed to such condition.

Mode of Use of Atroveran Compound

  • Tablet:
    • 2 to 3 tablets. Not to exceed the maximum dose of 8 tablets per day.
  • Solution:
    • 40 drops in a cup of water, 10 minutes before meals, two to three times a day.
    • In special cases, doses will be increased, which can be 40 to 80 drops at a time. The children will take half or the third of the indicated dose, according to each case.

Use in Pregnancy and Lactation

In pregnant patients, Papaverine Hydrochloride (active substance in this medicine) should only be prescribed in cases of extreme need.This recommendation is especially applicable in the last three months of pregnancy, as it is not proven that the use of the product during this period is without risk and, therefore, should only be done under careful medical evaluation.

The effects on the infant, if any, are not known. Therefore, administration to breastfeeding women should only be performed according to careful medical evaluation.

by Abdullah Sam
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