The Paracetamol acts on the nervous system by altering the perception of pain by the body primarily through the action of receptors by serotonin , the opioids and cannabinoids . Hence, it is an analgesic , i.e. a pain inhibitor. It is an antipyretic because it inhibits the synthesis of the molecules responsible for inflammatory processes (prostaglandins), and therefore lowers body temperature .
What is Paracetamol used for?
Paracetamol is used to counteract mild to moderate pain associated with headache , muscle discomfort, menstrual cycle, cooling syndromes, sore throat, toothache, back pain, osteoarthritis and reactions to vaccinations. Its frequent use is to lower the fever .
It can also be used to reduce migraine pain if it is taken in combination with aspirin and caffeine .
How is Paracetamol taken?
Paracetamol can be taken in the form of tablets, chewable tablets, capsules, suspensions, solutions, prolonged-release tablets or tablets that dissolve in the mouth, then orally . It is also possible to take it rectally, in the form of suppositories.
Side effects of Paracetamol
Taking too much Paracetamol can damage the liver.
A doctor should be contacted immediately if taking the drug is associated with:
- redness of the skin, exfoliation or blistering
- difficulty swallowing
- breathing difficulties
- swelling of the face, throat, tongue, lips , eyes, hands, feet, ankles or calves
- urticaria
- itch
- rash
- hoarseness
Contraindications and warnings on the use of Paracetamol
Before administering Paracetamol to pediatric patients, it is advisable to check that the medicine available is suitable for pediatric use . It is always a good practice, regardless of this, to seek advice from your doctor , and it is essential to avoid giving Paracetamol to children with headache, rash, nausea or vomiting or severe sore throat associated with vomiting. These symptoms may signal a problem that requires different types of treatment.
To use Paracetamol safely is essential :
- do not take several Paracetamol-based products at the same time;
- follow the dosage indicated on the package insert or by the doctor and never exceed 4,000 mg per day;
- do not exceed 2 doses of alcohol per day.
Your doctor should always be informed in case of:
- liver problems (also in the past);
- phenylketonuria ;
- allergies to the active substance, its excipients or other drugs;
- taking other medicines, herbal medicines or supplements at the same time, remembering to mention anticoagulants, anticonvulsants, painkillers, antipyretics, medicines for coughs and colds and phenothiazines;
- you are pregnant or breastfeeding .
