What is Aceclofenac?

Aceclofenac is recommended for the treatment of pain and inflammation related to osteoarthritis , rheumatoid arthritis and ankylosing spondylitis.It is a nonsteroidal anti-inflammatory medicine (Fans). It works by blocking the cyclooxygenase enzymes, thus preventing the formation of molecules (prostaglandins) included in the generation of pain, swelling and inflammation.

How is Aceclofenac taken?

Orally administered in the form of tablets , twice a day.

Side effects of Aceclofenac

Taking Aceclofenac may be associated with an increased risk of thrombosis, inhibit platelet aggregation and cause skin reactions. In addition, it can affect female fertility.

Among its other possible side effects we also find:

  • anemia , hemolytic anemia
  • immune system depression
  • granulocytopaenia
  • neutropenia
  • hyperkalemia
  • depression
  • strange dreams
  • insomnia
  • visual disturbances
  • paresthesia
  • tremors
  • drowsiness
  • headache
  • changes in taste
  • heart failure
  • palpitations
  • dizziness
  • tinnitus
  • hypertension
  • redness or flushing
  • vasculitis
  • dyspnoea
  • dyspepsia
  • abdominal pain
  • nausea
  • diarrhea
  • flatulence
  • gastritis
  • constipation
  • He retched
  • oral ulcers
  • melena
  • gastrointestinal bleeding and ulcers
  • stomatitis
  • increased symptoms of Crohn’s disease and ulcerative colitis
  • hematemesis
  • pancreatitis
  • Bullous dermatitis or dermatitis
  • angioedema
  • purple
  • leg cramps
  • increase in urea or creatinine in the blood
  • kidney failure
  • nephrotic syndrome
  • kidney failure
  • increase in liver enzymes
  • edema
  • fatigue
  • weight gain

It is essential to notify the doctor immediately in the presence of:

  • skin rash
  • urticaria
  • itch
  • breathing problems
  • feeling of tightness in the chest
  • swelling of the mouth, face, lips or tongue
  • jaundice

Contraindications and warnings

Aceclofenac is not indicated during pregnancy, specifically in the third trimester.

Before administering it, it is essential to notify the doctor:

  • of possible allergies to the active substance, to its excipients, to any other medicine (specifically to other NSAIDs), to foods or other drugs;
  • if you are taking phytotherapy and some supplements, specifically other NSAIDs or analgesics, diuretics, antihypertensives, cardiac glycosides, lithium, digoxin, methotrexate, mifepristone, corticosteroids, anticoagulants, antibiotics (in particular quinolones), anti-platelets, SSRIs, cyclosporine, tacrolimus, zidovudine and antidiabetics;
  • if there is a personal history of peptic or bleeding ulcers, bleeding, bleeding diathesis, bleeding or haematological disorders, congestive heart failure, ischemic diseases, cerebrovascular diseases, peripheral arterial disease, liver or kidney failure, bleeding or gastrointestinal perforation related to taking Fans, bronchial asthma, hypertension, ulcerative colitis, Crohn’s disease and systemic lupus erythematosus;
  • in the event of pregnancy or breastfeeding.

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