What is Cholestyramine?

The cholestyramine works by reducing cholesterol values. In addition, it is used to reduce the itching caused by partial obstructions of the biliary tract.

What is Cholestyramine?

Cholestyramine is a bile acid sequestering agent : it works by increasing the elimination of bile acids. This leads to their new production, in which the body uses the cholesterol present in the blood. The result is a reduction in blood cholesterol levels.

How is cholestyramine taken?

In general, cholestyramine is taken orally, in the form of a powder. Its intake must be combined with an appropriate diet.

Side effects of cholestyramine

A side effect commonly found while taking cholestyramine is constipation. If necessary, you can ask your doctor for a remedy to help you cope.

Instead, you should immediately contact a doctor in case of:

  • rashes
  • urticaria
  • itch
  • breathing difficulties
  • chest pain or tightness
  • swelling of the mouth, face, lips or tongue
  • stools dark or with blood
  • skin, tongue or anal area irritations
  • severe or persistent constipation
  • strong or persistent nausea
  • shortness of breath
  • indolence
  • stomach ache
  • bruising or bleeding
  • He retched

Contraindications and warnings

Some cholestyramine formulations can be sources of phenylalanine and therefore be contraindicated in the case of phenylketonuria. In addition, this active substance should not be taken in case of complete obstruction of the bile ducts (bile transport routes), severe constipation, high levels of chlorine in the blood or if you are already taking leflunomide or mycophenolate.

Cholestyramine can impair your ability to drive and operate dangerous machinery, especially when taken together with alcohol or other medicines. In addition, it can interfere with the effectiveness of hormonal contraceptives.

Before starting treatment it is important to tell your doctor:

  • of allergies to the active substance, its excipients or to other drugs or foods;
  • of medicines, officinal drugs and supplements taken, citing in particular anticoagulants, beta blockers, deferasirox, digoxin, digitoxin, diuretics, estrogens, hormonal contraceptives, leflunomide, mycophenolate, penicillins, phenobarbital, phenylbutazone, phosphates, progestin, tetracline spironolactone;
  • if you suffer (or have suffered) from heart disease, constipation, hemorrhoids , gastrointestinal blockages, gallbladder problems, blood disorders, bleeding or coagulation, high triglycerides, intestinal and malabsorption problems, kidney disease, phenylketonuria, diabetes, hypothyroidism, liver disease, alcohol dependence, dehydration or hypovolemia;
  • if you are pregnant or breastfeeding.

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