Catalytic asymmetric oxidation. It is a technique used in organic chemistry to oxidize various substrates to give an enantiomerically pure product through the use of catalysis.
Oxidation
This process that occurs in an element when it is oxidized, is a state reached when oxygen or any other oxidizing agent generates oxide when reacting with a substance. According to the vocabulary of the field of Chemistry , this arises when an atom or ion loses electrons , a circumstance that, on the one hand, causes a certain substance to oxidize and, on the other, leads to another being reduced.
One type of oxidation is catalytic asymmetric oxidation, a technique that allows various substrates to be oxidized to generate an enantiomerically pure product.
Best known reactions
Within this family of reactions, the best known are:
- Jacobsen epoxidation of alkenes using manganese complex and ligand leave and NaOCl.
- Sharpless epoxidation of allyl alcohols using titanium isopropoxide, diethyl tartrate, and t-butyl hydroxoperoxide.
- Sharpless asymmetric dihydroxylation of alkenes using dihydroquinine or dihydroquinidine ligands around an osmium metal center.
- Sharpless oxyamination.
- Shi epoxidation of alkenes using oxone and a chiral catalyst derived from fructose.
- Sulfonyloxaziridine enolate oxidation.
