Bitter orange is a plant whose fruits, flowers and leaves are used for medicinal purposes.
What is bitter orange used for?
Bitter orange contains compounds that can influence the functioning of the nervous system and the narrowing of blood vessels , the increase in blood pressure and heart rate.
For these properties, it is proposed in the form of supplements and products to be applied to the skin. In particular, it is suggested to promote both appetite and weight loss, against stomach problems, nasal congestion and chronic fatigue syndrome, gastrointestinal problems such as constipation, diarrhea and flatulence, to control blood sugar and lipid levels, to promote cardiovascular health and against liver, gallbladder, kidney and bladder diseases. There are also those who take it against anemia, eye problems, chilblains, muscle, joint and nerve pain. However, the scientific evidence currently available suggests real effectiveness only in the case of topical application for the treatment of skin infections.
Warnings and possible contraindications
Bitter orange may interfere with the intake of some drugs against depression (MAO inhibitors) and with midazolam. It may also interfere with caffeine, dextromethorphan, felodipine, indinavir and drugs metabolized by cytochrome P450 3A4, those that prolong the QT interval and stimulants. The
safety of bitter orange is questioned when it is taken for weight loss, especially if combined with stimulants such as caffeine: the risk of high blood pressure, fainting, heart attacks, strokes and other serious side effects may in fact increase significantly. In addition, cases of headaches triggered by the intake of bitter orange have been reported. Finally, bitter orange increases sensitivity to the sun, may interfere with blood sugar control in those with type 2 diabetes, may aggravate glaucoma, and may be contraindicated in cases of QT prolongation, high blood pressure, arrhythmias, and scheduled surgery. If in doubt, it is best to consult your doctor.
