The Domperidone is a specific inhibitor of the receptor dopamine neurotransmitter .
It works by promoting the emptying of the digestive system, stimulating the contraction of the esophagus and stomach and reducing the pressure of the esophageal sphincter (between stomach and esophagus)
In addition, by blocking the activity of these receptors, it also performs an action against nausea .
What is Domperidone used for?
Domperidone is used to manage digestive difficulties , heartburn , epigastric pain, nausea and vomiting .
How is Domperidone administered?
Domperidone is administered orally in the form of tablets to be taken 15 to 30 minutes before meals.
Side effects of Domperidone
Possible adverse effects of Domperidone include:
- milk production from the nipples (also in men);
- increase in the volume of the mammary gland;
- in men, decreased libido;
- vision problems;
- balance problems.
It is good to contact a doctor immediately in case of:
- swelling of the hands, feet, ankles, face, lips or throat;
- difficulty swallowing or breathing;
- urticaria ;
- heart beat abnormalities, especially increases in frequency;
- uncontrolled movements of the eyes or tongue;
- neck twist;
- muscle stiffness;
Warnings on the use of Domperidone
Domperidone must not be taken together with Ketoconazole, Erythromycin, Telaprevir or Titonavir.
It is also important to inform your doctor before taking it:
- of allergies to the active substance, its excipients or other drugs;
- medicines, officinal drugs and supplements taken, citing in particular Cimetidine, Cabergoline, Bromocriptine, Artemether, Tacrolimus, Tiotixene, Toremifene, Trimipramine, Vorinostat, Ziprasidone and Zuclopentixol;
- if you suffer (or have suffered) from cardiovascular problems, prolactinoma (tumor of the pituitary gland), ulcers, strong and frequent stomach cramps, intestinal blockages, kidney, liver or intestinal disorders;
- if you are pregnant or breastfeeding .
It is also necessary to inform surgeons and dentists if Domperidone is taken.