Pharmacological abortion

pharmacological abortion. The different methods of pharmacological abortion eliminate the classic complications of surgical abortion, either in its traditional version: instrumental curettage with general anesthesia or in its current version (still unknown in many hospitals), intrauterine aspiration with plastic material and local anesthesia.

Summary

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  • 1 Definition
  • 2 Pharmacological methods
  • 3 Contraindications
    • 1 Do not forget to mention
  • 4 Instructions for use
  • 5 Medical abortion
  • 6 side effects
  • 7 Advantages
  • 8 Bibliographic References
  • 9 external links

Definition

Pharmacological methods suppose a greater degree of intimacy and autonomy, in addition to reducing the physical and psychological trauma that an act such as abortion always entails, which for any woman is always traumatic to some extent. It seems to be, without a doubt, that the most effective method to abort would be the combination of Mifepristone plus Misoprostol

Pharmacological methods

  • Mifepristone (RU486, Myfegyn, Mifeprex) + misoprostol: It is the best method of the 4, in terms of efficacy, safety and comfort.
    • For its use, it must be a pregnancy of less than 49 days or (7 weeks), counted from the first day of the last period (contraindicated in pregnancies of more than 50 days of amenorrhea)

Contraindications

  • Ectopic pregnancy (extra-uterine).
  • Allergy to mifepristone or misoprostol.
  • Chronic use of systemic corticosteroids.
  • Chronic adrenal failure.
  • Coagulopathy or anticoagulant therapy.
  • hereditary porphyria.
  • Hypertension , severe liver or kidney disease, and severe anemia should be evaluated on an individual basis.
  • If an intrauterine device (IUD) is present, it should be removed prior to treatment.

Don’t forget to mention

  • Have you had or have: diabetes ; hypertension; porphyria; suprarrenal insufficiency; or heart , kidney , liver , or lung disease .
  • Use an intrauterine device (IUD).
  • If you are breastfeeding.
  • If you are having any surgery, including dental surgery, tell the doctor or dentist that you are taking mifepristone.
  • If you smoke 10 or more cigarettes a day or if you have a history of smoking.

How to use

It should be taken only in a clinic or hospital under the supervision of the doctor. You will need to take 3 mifepristone tablets on the first day, 2 days later if the doctor cannot confirm if the pregnancy has ended, you will need to take 2 misoprostol tablets.

After 14 days of taking mifepristone, you will need to see your doctor for an exam or ultrasound to confirm that the pregnancy has ended. At the end of treatment you should take precautions not to become pregnant.

pharmacological abortion

  • Methotrexate + Misoprostol: This method is widely used in Canada and other countries where mifepristone is not yet marketed. In Europe it is not used.
  • Misoprostol alone (Cytotec, Arthrotec, Oxaprost, Cyprostol, Mibetec ou Misotrol): Misoprostol alone is illegal and widely misused by thousands of immigrant women and also in countries without induced abortion legislation, each year. It is not used in authorized centers. In cases where, after using misoprostol alone and the abortion has been unsuccessful, the pregnancy must be terminated surgically (due to the risk of congenital malformations).
  • Oxytocin alone: ​​This method is partially pharmacological, since a surgical act is performed after expulsion (performing an aspiration and curettage)

Side effects

  • Shaking chills
  • diarrhea
  • vomiting
  • Fever
  • dizziness
  • headache
  • Heat
  • redness
  • Skin rash

Advantage

The different methods of pharmacological abortion eliminate the classic complications of surgical abortion, that is, the danger of uterine perforations, cervical tears, Asherman’s syndrome, infections, etc., since no instrument is inserted into the uterine cavity. On the other hand, pharmacological methods imply a greater degree of intimacy and autonomy. It seems to be, without a doubt, that the most effective method for abortion would be the combination of mifepristone + misoprostol, reaching complete abortion rates that range between 96% and 99%, both in abortions in the first and second trimesters of pregnancy. In addition, the use of these pharmacological methods, especially misoprostol alone, is contributing significantly to reducing mortality from abortion performed in unsafe conditions,Third World .