Is Mefenamic Acid Safe for Pregnant Women?

Mefenamic acid is a pain reliever that is commonly used to treat minor pain, inflammation, and fever. Although it is effective in overcoming this condition, the use of mefenamic acid for pregnant women cannot be arbitrary. So, how safe is mefenamic acid for pregnant women?

Mefenamic acid for pregnant women is not necessarily safe

Pregnant women do have limitations in taking drugs, including pain relievers such as mefenamic acid.Mefenamic acid is a class of nonsteroidal anti-inflammatory drugs or NSAIDs that aim to treat pain, inflammation, and fever.Mefenamic acid works by reducing levels of prostaglandins, which are hormones that cause pain and inflammation in the body.For some people, mefenamic acid is an option for treating toothaches, headaches, menstrual pain, and arthritis.

Mefenamic acid consumption for pregnant women must be according to a doctor’s prescription

Although it is effective in overcoming this condition, the use of mefenamic acid for pregnant women, especially at 30 weeks of gestation or more, tends to be unsafe unless prescribed by a doctor.This is because mefenamic acid for pregnant women is classified as a category C drug by the US Food and Drug Administration (FDA).This means that these drugs can be consumed provided that the benefits obtained are greater than the risk of harming the fetus in the womb.If you are 30 weeks pregnant or more and have already taken mefenamic acid, you should tell your doctor immediately.

What are the possible risks of consuming mefenamic acid for pregnant women?

The placental blood vessels close so a side effect of mefenamic acid for pregnant women

Mefenamic acid for pregnant women tends to be unsafe for consumption, especially in third trimester of pregnancy.Some of the risks that may arise due to the use of mefenamic acid for pregnant women are as follows:

1. The placental blood vessels close

One of the risks of using mefenamic acid for pregnant women is the placental blood vessels that close faster.This is because in the uterus, the blood vessels in the placenta must remain open to deliver nutrients and oxygen from mother to fetus.Consumption of mefenamic acid for pregnant women can trigger the closure of the ductus arteriosus, which is a blood vessel that plays an important role in blood transport, oxygen and nutrition for the fetus.This closure of the blood vessels results premature birth and other fetal problems.

2. Oligohydramnios

Just like the NSAID class in general, the use of mefenamic acid for pregnant women has the risk of causing oligohydramnios.Oligohydramnios is a condition in which the amount of amniotic fluid surrounding the fetus in the uterus is too little.

3. Neonatal persistent pulmonary hypertension

Although rare, neonatal persistent pulmonary hypertension or PPHN is also a risk of using mefenamic acid for pregnant women.Neonatal persistent pulmonary hypertension is a condition when a newborn’s circulatory system is unable to adapt to breathing outside the womb.In some cases, this condition can be caused by closing blood vessels in the placenta.Several small-scale studies have shown an association between PPHN and NSAID use during pregnancy.However, further research is still needed on the relationship between PPHN and NSAIDs, especially mefenamic acid.In addition, mefenamic acid is believed to interfere with female fertility. Therefore, women who are planning a pregnancy should not take this drug.

Pain relievers for pregnant women that are safe to consume

If the pain, inflammation, or fever is unbearable during pregnancy, the doctor may recommend that pregnant women use pain relievers other than mefenamic acid to avoid the risk of harm to the fetus.Mefenamic acid substitute for pregnant women that is classified as safe for consumption is paracetamol.Paracetamol for pregnant women can be used to control pain, inflammation, or fever during pregnancy.

Paracetamol for pregnant women tends to be safe for consumption

However, it is important to consume paracetamol for pregnant women with the lowest possible dose and in a short time.If paracetamol can not control relieve pain, inflammation, or fever that you experience, consult a doctor immediately. The doctor will provide recommendations for pain relievers for pregnant women that are safe or diagnose the cause correctly.

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