Feverfew: 17 properties, benefits and contraindications

The feverfew, Tanacetum parthenium or Chrysanthemum parthenium Berhn. or Matricaria parthenium L. , of the family Asteraceae (Compositeae).It is a small plant that reaches one meter in height.

17 properties of the partnership

Parthenon is considered in herbal medicine the best product for migraine, rheumatism and premenstrual syndrome. Numerous studies on Parthenolide, a component of Parthenone, confirm the anti-inflammatory activity and more. Now let’s find out in detail all its benefits:

  1. The parthenon contains flavonoids such as quercetin, luteolin, apigenin and axillarin which has spasmolytic action (calms muscular contractions from spasms) on the smooth muscles of the gastrointestinal tract.
  2. Sesquiterpenes lactone compounds, such as parthenolide, modulate the functions of the serotonin system, for this reason they are believed to prevent migraine.
  3. The parthenon also contains tannins and heterosides that have anti-inflammatory properties, essential oil with camphor and bitter substances.
  4. The partnership plant is considered one of the most effective in alleviating migraine.
  5. It does not cure migraines but provides temporary relief. Although its properties have not yet been officially recognized, feverfew is believed to reduce secondary symptoms such as nausea and frequency of episodes.
  6. Its action consists in the ability to inhibit the release of arachidonic acid (precursor in the synthesis of eicosanoids) involved in the synthesis of prostaglandins, substances that intervene in inflammatory processes. The production of arachidonic acid derivatives is known, on the whole, as the arachidonic acid cascade. It also inhibits the synthesis of many cytokines also involved in inflammation.
  7. As an anti-inflammatory it is used in the treatment of arthritic pain.
  8. It contains an essential oil with spasmolytic action (which calms spasms) and is therefore indicated in premenstrual syndromes: it relaxes the smooth muscles calming the contractions of the uterine musculature constituting a valid aid in case of dysmenorrhea (painful menstruation).
  9. Its antispasmodic action on smooth muscles also has an effect on gastric walls.
  10. It possesses emmenagogue properties, that is it favors menstruation.
  11. The parthenonol, thanks to the parthenolide, is endowed with inhibitory properties against platelet aggregation due also to the inhibitory action of the release of serotonin of the same platelets.
  12. Numerous studies have been carried out on feverfew and in particular the immunological, rheumatological and oncological interest has focused on one of its components: parthenolide.
  13. Its anti-inflammatory property has been confirmed by studies in animals, human tissues or in vitro. Research, not supported by clinical trials and still requiring official recognition, needs further investigation on human samples.
  14. A study conducted by the Department of Chemistry and Oncology of the University of Rochester (USA) highlighted the promising anticancer activity of Parthenolide as a natural product ( 1)
  15. Still in the oncological field, a study carried out on hamsters investigated the chemotherapy preventive potential of parthenolide in DMBA-induced oral carcinogenesis (dimethylbenzantracene, polycyclic hydrocarbon used in medical research). The results suggest that parthenolide is not only protective chemo, but also possesses antioxidant and apoptotic properties ( 2). This research by the Department of Pharmaceutical Science of the University of Juiz de Fora (Brazil) studied the immunomodulatory effects of in vitro parthenolide on cytokine production ( 3 ).
  16. Also other studies, again on animal guinea pigs, confirm the anti-inflammatory and antioxidant activity of parthenolide. The one conducted by the Faculty of Medicine of the University of Hamdan, in Iran, explored the action of the parthenolide on non-alcoholic liver disease on rats ( 4).
  17. Positive studies, not supported by clinical trials, on the anticancer activity of parthenolide concern certain types of cancer such as gastric carcinoma, pulmonary carcinoma, prostate cancer and multiple myeloma.

When it is useful and what are the applications

The phytotherapeutic preparations that contain fever are used to treat: migraine, rheumatism and neuralgia.

The properties of feverfew are largely due to the sesquiterpene content, in particular to parthenolide and flavonoids.

The uses of partnership:

  • The feverfew is used in the form of t Isana: Pour 100 ml of boiling water over 2 g of leaves, cover and leave to infuse for 10 minutes. Only.
  • It is found in the form of mother tincture, already prepared, in herbalist’s shops. The mother tincture is obtained by macerating the leaves, harvested in July and August, in a mixture of food alcohol and water for three weeks, squeezed and filtered.
  • The dry extract is obtained by evaporating the mother tincture and is found in tablets or capsules. The capsules or tablets are the most used and preferable form due to the bad taste of the plant.
  • The powder is obtained by crushing the dried leaves.

The plant

Perennial and very aromatic herbaceous plant does not reach the meter and has flowers very similar to the daisy: inflorescences with dense yellow heads, but with an unpleasant smell, corolla of petals in the shape of white and leaf-shaped tabs, oval and pennatosette, yellow-green.

The Its leaves are harvested when they are fully developed, between July and September.

The drug that is the part of phytotherapic interest is constituted by the aerial parts.

Feverfew is very similar to chamomile and chrysanthemum, it appears as a cross, but care must be taken not to confuse it with the toxic Tansy (Tanacetum vulgare L., sin Chrysantemum vulgare Bernhardi) or with the pyrethrum or American Chrysanthemum and with other species of toxic tans, whose overdose can be fatal.

It does not have particular cultivation requirements, it propagates by seed before the temperature drops and in a sunny position.

Collection and storage

The flowering tops are cut in summer, June / July, and dried in a shady and ventilated place.Preserves away from light and humidity.

Contraindications and warnings:

Seek the advice of the attending physician before starting a therapy with the partnership. Parthenion can hinder blood clotting, so it is contraindicated for those who have problems with coagulation, gastritis or ulcers. Do not take in case of hypersensitivity to Asteraceae. It is not recommended in pregnancy and lactation and in children. It can give rise to disorders such as vomiting, diarrhea, headache, insomnia and allergic dermatitis in case of contact with the fresh plant in people with hypersensitivity. Drug interactions with antiplatelet agents,

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