Baricitinib is a substance that reduces the response of the immune system, decreasing the action of enzymes that promote inflammation and the appearance of joint damage in cases of rheumatoid arthritis. In this way, this remedy is able to reduce inflammation, relieves the symptoms of the disease like pain and swelling of the joints.
What Baricitinib Is Used For
Baricitinib is indicated for the treatment of severe rheumatoid arthritis, where the symptoms do not improve with the use of other antirheumatic drugs.Baricitinib may be used as a single medicine or together with other medicines, such as methotrexate.
Baricitinib works by reducing the activity of an enzyme called Janus kinase, which is involved in inflammation. By reducing the activity of this enzyme, it helps to reduce the pain, stiffness and swelling of your joints,and decrease the progression of lesions in bone and joint cartilage. These effects can help you to perform your normal daily activities and thereby improve the health-related quality of life of patients with rheumatoid arthritis.
How To Take Baricitinib
Treatment with baricitinib should always be directed by a physician, however, the indicated starting dose is 4 mg once daily.However, this dose can be lowered to 2 mg per day when inflammation is controlled.
Possible side effects
The use of this medicine can cause some side effects such as nausea, acne, weight gain and more frequent onset of respiratory infections. In addition, some patients may also have abnormal blood tests, especially in the number of platelets and neutrophils.
Who should Not Use Baricitinib
Baricitinib is contraindicated for pregnant women and people who are hypersensitive to any of the ingredients in the formula.In addition, this drug should be used with caution, and to a lesser extent, in elderly children and patients with liver or kidney disease.
Undesirable / Adverse EffectsInfection as the zone, which can affect up to 1 in 10 people:
Tell your doctor immediately or seek medical help if you experience the following symptoms, which may be signs of a herpes zoster:
– Painful rash with blisters and fever
Effects very common (may affect more than 1 in 10 people):
– throat and nose infections
– high levels of blood fat (cholesterol) revealed by a blood test Common
side effects (may affect up to 1 in 10 people):
– thrush (herpes simplex)
– infection leading to stomach pain or diarrhea (gastroenteritis)
– urinary infection
– high number of platelets (cells involved in blood clotting) revealed by a blood test
– feeling sick to the stomach (nausea)
– high levels of liver enzymes revealed by a blood test.
– If you forget to take this medicine, take it as soon as you remember
– If you forget to take it for an entire day, skip the missed dose and take a single dose the next day , as usual.
– Do not take a double dose to make up for a forgotten tablet.